Navigating the Nephron with Novel Hyper-Characterized Organoids
Novel nephron organoids have been developed, which can be fine-tuned to represent the proximal convoluted tubule or loop of Henle.
You're on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can't handle it. You're harming them.
This scenario has driven Nils Lindstrom, leader of a lab at the University of Southern California, on a decade-long journey to better understand the nephron and its cells.
Lindstrom's work aims to improve understanding of the kidney's functional unit, driven by the need to protect patients from harm.
Author's summary: Novel organoids help understand kidney function.
- Novel nephron organoids developed
- Represent proximal convoluted tubule or loop of Henle
- Leader of lab at University of Southern California
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